CD300b/LMIR5/CD300LB Fc Chimera Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	CD300b Protein, Human; CLM-7 Protein, Human; CLM7 Protein, Human; CMRF35-A2 Protein, Human; IREM-3 Protein, Human; IREM3 Protein, Human; TREM-5 Protein, Human; TREM5 Protein, Human
Accession	AAH28091
Amino Acid Sequence	Ile55-His187, with C-terminal hIgG1 Fc
Expression System	HEK293
Molecular Weight	48-53kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Tag	Human Fc Tag
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4.
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Journal List Cell Death Differ v.21(11); 2014 Nov PMC4211373.

Background

The CD300 receptor family members are a group of molecules that modulate a variety of immune cell processes. The CD300 receptor family consists of members with activating and inhibitory capabilities mainly expressed on the surface of immune cells. LMIR5, also known as CD300b, CD300LB, CLM-7, and IREM‑3, is a glycoprotein member of the immunoglobulin superfamily. Human LMIR5 consists of a 134 amino acid (aa) extracellular domain (ECD) with one Ig-like V-type domain, a 21 amino acid (aa) transmembrane segment, and a 29 aa cytoplasmic domain. Studies have shown that CD300b recognizes PS as a ligand and regulates phagocytosis of apoptotic cells through DAP12 signaling pathway.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.