Neural cell adhesion molecule L1, also known as L1CAM, is a crucial glycoprotein in the nervous system. It belongs to the immunoglobulin superfamily of cell adhesion molecules. L1 plays a vital role in various neural processes, including neuronal migration, axonal outgrowth, and synapse formation. It mediates cell - cell adhesion through homophilic and heterophilic interactions, which are essential for the proper development and function of the nervous system. Mutations in the L1CAM gene can lead to several neurological disorders, such as X - linked hydrocephalus, mental retardation, and spastic paraplegia, highlighting its significance in maintaining normal neural function.
中文
