NOTCH2 Fc Chimera Protein, Human,UA BIOSCIENCE_specification/price/image

Product Detail
Company Profile

Product Specification

Species	Human
Synonyms	NOTCH2, hN2, N2ECD
Accession	Q04721
Amino Acid Sequence	Leu26-Gln530, with C-terminal hIgG1 Fc
Expression System	HEK293
Molecular Weight	85-93kDa (Reducing)
Purity	＞95% by SDS-PAGE
Endotoxin	<0.1EU/μg
Conjugation	Unconjugated
Physical Appearance	Lyophilized Powder
Storage Buffer	PBS, pH7.4.
Reconstitution	Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage	· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles.
Reference	1.Gene ID: 4853, updated on 12-Dec-2023.

Background

Human Notch-2 is a 300 kDa type I transmembrane glycoprotein. Members of this Type 1 transmembrane protein family share structural characteristics and play a role in a variety of developmental processes by controlling cell fate decisions. As a receptor for the membrane-binding ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1), the ligands, activated by the released notch intracellular domain (NICD), form a transcription activator complex with RBPJ/RBPSUH to activate the division site enhancer gene.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.