Stat6 protein, which stands for Signal Transducer and Activator of Transcription 6, is a crucial component in the immune system. It is a member of the Stat family of transcription factors that play key roles in transmitting signals from cytokine receptors to the nucleus. When activated by cytokines like IL-4 and IL-13, Stat6 translocates to the nucleus and regulates the expression of numerous genes involved in immune responses, such as those related to the differentiation of T helper 2 cells and the production of immunoglobulin E. This protein is essential for mounting effective immune responses against certain pathogens and also has implications in various immune-related diseases, including asthma and allergic reactions.
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