Phospho-Histone H3 (Ser10) Recombinant Rabbit mAb (S-960-58),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	Phospho-Histone H3 (Ser10)
Synonyms	H3S10P
Immunogen	Synthetic Peptide
Location	Nucleus
Accession	P68431
Clone Number	S-960-58
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, ChIP
Reactivity	Hu, Ms, Rt
Predicted Reactivity	Ar, Bv, C.el, Dr, Hm, Or, Xe, Ys
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 掳C as supplied

Dilution

application	dilution	species
Dot Blot	1:10000
WB	1:20000	Hu, Ms, Rt
ChIP	1:20-1:50	Hu, Ms, Rt

Background

Phospho-Histone H3 (Ser10) is a critical epigenetic marker associated with chromosome condensation and mitotic progression. This phosphorylation event typically occurs during the G2 to M phase transition and is essential for chromatin condensation, making it a specific indicator of mitotic cells. It is regulated by kinases such as Aurora B and plays a significant role in mitotic chromosome condensation and decondensation. Additionally, H3 Ser10 phosphorylation has been implicated in transcriptional regulation and early gene expression, and its dysregulation has been linked to neoplastic cell transformation and cancer.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.