nmt55/p54nrb Recombinant Rabbit mAb (S-1745-48),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	nmt55/p54nrb
Synonyms	Non-POU domain-containing octamer-binding protein; NonO protein; 54 kDa nuclear RNA- and DNA-binding protein (p54(nrb); p54nrb); 55 kDa nuclear protein (NMT55); DNA-binding p52/p100 complex, 52 kDa subunit; NONO; NRB54
Immunogen	Synthetic Peptide
Location	Nucleus
Accession	Q15233
Clone Number	S-1745-48
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, ICC
Reactivity	Hu, Ms, Rt
Positive Sample	HeLa, 293T, Jurkat, MCF7, Molt-4, PC-3
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000	Hu, Ms, Rt
IHC-P	1:1000	Hu, Ms, Rt
ICC	1:500	Hu

Background

p54nrb, also known as NONO, is a multifunctional nuclear protein that plays a role in various nuclear processes, including transcriptional control, RNA splicing and editing, and DNA unwinding and pairing. It is involved in the nuclear retention of defective RNAs and RNA transport, and its disruption can lead to expressional changes of tumorigenic genes and decreased stress tolerance, resulting in increased cell death susceptibility in human tumor cells. Additionally, p54nrb is multiphosphorylated during mitosis and interacts with the mitotic regulator Pin1, suggesting its involvement in cell cycle regulation.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.