Phospho-PDHA1 (S293) Recombinant Rabbit mAb (S-1729-25),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	Phospho-PDHA1 (S293)
Synonyms	Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial; PDHE1-A type I; PHE1A
Immunogen	Synthetic Peptide
Location	Mitochondrion
Accession	P08559
Clone Number	S-1729-25
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P
Reactivity	Hu, Ms, Rt
Positive Sample	HepG2, HEK-293, HeLa, NIH/3T3, mouse brain, PC-12, Rat brain
Predicted Reactivity	Bv, CyMk, Or, Pg
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
Dot Blot	1:1000
WB	1:1000	Hu, Ms, Rt
IHC-P	1:500	Hu, Ms, Rt

Background

PDHA1, or pyruvate dehydrogenase E1 subunit alpha 1, is a crucial component of the pyruvate dehydrogenase complex (PDHc), which is a mitochondrial multienzyme complex that catalyzes the conversion of pyruvate to acetyl-CoA and CO2, providing a primary link between glycolysis and the tricarboxylic acid (TCA) cycle. Phosphorylation of PDHA1 at Ser293 (PDHA1 phospho S293) is an important regulatory modification that affects the activity of the PDH complex, which is crucial for the regulation of glucose metabolism and fatty acid oxidation, which are sensitive targets for insulin action.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.