Invivo anti-Mouse CD8α Recombinant mAb,Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rat
Antigen	CD8α
Synonyms	Lyt-2
Location	Cell membrane
Accession	P01731
Clone Number	S-R540
Antibody Type	Rat mAb
Isotype	Rat IgG2a,k
Application	in vivo CD8+ T cell depletion
Reactivity	Ms
Purification	Protein G
Concentration	5 mg/ml
Endotoxin	<2EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Background

CD8α encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.