Beta IV Tubulin, also known as tubulin beta 4A class IVa or TUBB4, is a specific isotype of beta-tubulin that plays a crucial role in the central nervous system. It is selectively expressed by oligodendrocytes, which are the cells responsible for myelination in the brain and spinal cord. This tubulin isotype is important for maintaining the structure and function of oligodendrocytes and their ability to form myelin. Myelin is a fatty substance that insulates nerve fibers and is essential for the proper conduction of nerve impulses. Beta IV Tubulin may also be involved in cell signaling pathways and gene expression patterns that change during oligodendrocyte differentiation and myelination.