Invivo anti-mouse Ly6G/Ly6C (Gr-1) (S-R425),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rat
Antigen	Mouse Ly-6G/Ly-6C (Gr-1)
Synonyms	Lymphocyte antigen 6G, Ly-6G.1
Location	Cell membrane
Accession	P35461
Clone Number	S-R425
Antibody Type	Recombinant mAb
Isotype	Rat IgG2b,k
Application	in vivo depletion of Gr-1+ myeloid cells
Reactivity	Ms
Purification	Protein G
Concentration	5 mg/ml
Endotoxin	<1EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Background

This antibody recognizes the same epitope as clone RB6-8C5. Ly-6G protein is a GPI (glycosylphosphatidylinositol)-anchored protein. Ly-6G is primarily expressed on monocytes, neutrophils, and T cells. It plays a crucial role in inhibiting anti-tumor efficacy and T-cell responses. Due to its specific expression on neutrophils, Ly-6G has been widely used as a surface marker in flow cytometry, cell sorting, and immune phenotyping experiments. Unique expression of Ly-6G in bone marrow indicates its involvement in hematopoietic microenvironment, potentially regulating the development or function of immune cells within the bone marrow niche.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.