LRRK2 (phospho S935) Recombinant Rabbit mAb (S-966-37),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	LRRK2 (phospho S935)
Synonyms	Leucine-rich repeat serine/threonine-protein kinase 2, Dardarin, PARK8
Immunogen	Synthetic Peptide
Location	Cytoplasm
Accession	Q5S007
Clone Number	S-966-37
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB
Reactivity	Hu
Predicted Reactivity	Ms, Pr, Rt, Pg
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
Dot Blot	1:1000
WB	1:1000

Background

LRRK2, also known as Leucine-rich repeat kinase 2, is a large, multi-domain protein kinase that belongs to the ROCO (Ras of complex proteins) family. It is highly conserved across species and plays important roles in various cellular processes, including vesicle trafficking, autophagy, and cytoskeletal dynamics. Mutations in the LRRK2 gene have been linked to several neurodegenerative disorders, most notably Parkinson's disease. The phosphorylation of LRRK2 at S935 has been implicated in modulating its kinase activity and may contribute to the pathogenesis of Parkinson's disease and other LRRK2-related disorders.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.