EpCAM Recombinant Rabbit mAb (Alexa Fluor® 488 Conjugate) (S-078-13),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	EpCAM
Synonyms	Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein (EGP), Epithelial glcoprotein 314 (EGP314; hEGP314), GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1, Ber-EP4
Immunogen	Synthetic Peptide
Location	Cell junction, Lateral cell membrane
Accession	P16422
Clone Number	S-078-13
Antibody Type	Recombinant mAb
Isotype	IgG
Application	ICC, IF
Reactivity	Hu
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Alexa Fluor® 488
Physical Appearance	Liquid
Storage Buffer	PBS, 0.1% BSA, 0.01% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
ICC	1:200	null
IF	1:200	null

Background

Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.