FABP7 protein is a highly expressed protein in the nervous systems of humans and animals. Structurally, it consists of 10 β-strand segments that form a three-dimensional structure enclosing a fatty acid binding pocket. It is mainly present in astrocytes and neural precursor cells in the adult nervous system. By binding to n-3 and n-9 polyunsaturated fatty acids (PUFAs), such as docosahexaenoic acid (DHA) and oleic acid, FABP7 regulates the metabolism of these fatty acids. FABP7 protein plays a crucial role in neural development, cell migration, and signal transduction. In the embryonic brain, it is essential for the maintenance and proliferation of neural stem progenitor cells and radial glial cells.
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