S-RMab® CD8α Mouse mAb (SDT-1036-34),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Mouse
Antigen	CD8α
Synonyms	T-lymphocyte differentiation antigen T8/Leu-2, T-cell surface glycoprotein CD8 alpha chain, MAL, CD8a
Immunogen	Recombinant Protein
Location	Cell membrane
Accession	P01732
Clone Number	SDT-1036-34
Antibody Type	Mouse mAb
Isotype	IgG1,k
Application	IHC-P, ICC, FCM, IF
Reactivity	Hu
Purification	Protein G
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:1000
ICC	1:500
IF	1:1000
FCM	1:2000

Background

CD8A encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.