PKM Recombinant Rabbit mAb (S-812-20),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Synonyms	Pyruvate kinase PKM, Cytosolic thyroid hormone-binding protein (CTHBP), Opa-interacting protein 3(OIP-3), Pyruvate kinase 2/3, Pyruvate kinase muscle isozyme, Threonine-protein kinase PKM2, Thyroid hormone-binding protein 1 (THBP1), Tumor M2-PK, Tyrosine-protein kinase PKM2, p58, OIP3 , PK2, PK3, PKM2
Immunogen	Synthetic Peptide
Location	Cytoplasm, Nucleus
Accession	P14618
Clone Number	S-812-20
Antibody Type	Recombinant mAb
Isotype	IgG
Application	WB, IHC-P, ICC, ICFCM, IP
Reactivity	Hu, Ms, Rt
Predicted Reactivity	Or, Ct, Rb
Purification	Protein A
Concentration	0.5 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000
IP	1:50
IHC-P	1:500
ICC	1:500
ICFCM	1:500

Background

Pyruvate kinase is the enzyme involved in the last step of glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to adenosine diphosphate (ADP), yielding one molecule of pyruvate and one molecule of ATP. In contrast to mitochondrial respiration, energy regeneration by pyruvate kinase is independent from oxygen supply and allows survival of the organs under hypoxic conditions often found in solid tumors. Pyruvate kinase is present in four distinct, tissue-specific isozymes in animals, each consisting of particular kinetic properties necessary to accommodate the variations in metabolic requirements of diverse tissues.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.