Invivo anti-mouse CTLA-4 (CD152) mAb,Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Mouse
Synonyms	Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4
Location	Cell membrane
Accession	P09793
Clone Number	9D9
Antibody Type	Recombinant mAb
Isotype	IgG2b,k
Application	WB, in vivo CTLA-4 neutralizatior
Reactivity	Ms
Purification	Protein A
Concentration	Lot specific* (generally 5 to 20 mg/ml)*
Endotoxin	<1EU/mg
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, containing no preservative
Stability & Storage	2 to 8 °C for 2 weeks under sterile conditions; -20 °C for 3 months under sterile conditions; -80 °C for 24 months under sterile conditions. Please avoid repeated freeze-thaw cycles.

Dilution

application	dilution	species
WB	1:1000

Background

This antibody recognizes the same epitope as clone 9D9.

Cytotoxic T-lymphocyte associated protein 4, (CTLA-4) also known as CD152 (cluster of differentiation 152), is a protein receptor that functions as an immune checkpoint and downregulates immune responses. CTLA-4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. CTLA-4 may also function via modulation of cell motility and/or signaling through PI3 kinase.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.