Protein NDRG2 is a protein that in humans is encoded by the NDRG2 gene (NMYC downstream-regulated gene 2). This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Protein NDRG2 is a cytoplasmic protein that may play a role in neurite outgrowth. This protein may also be involved in glioblastoma and aggressive meningioma carcinogenesis (via cell proliferation).