CD8α Recombinant Rabbit mAb (Alexa Fluor® 647 Conjugate) (SDT-142-52),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	CD8α
Synonyms	Lyt-2
Immunogen	Synthetic Peptide
Location	Cell membrane
Accession	P01731
Clone Number	SDT-142-52
Antibody Type	Recombinant mAb
Application	FCM, IF
Reactivity	Ms
Purification	Protein A
Concentration	2 mg/ml
Conjugation	Alexa Fluor® 647
Physical Appearance	Liquid
Storage Buffer	PBS, 0.1% BSA, 0.01% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
IF	1:200
FCM	1:200

Background

CD8α encodes the CD8 alpha chain of the αβT cells, proposed as a quantifiable indicator for CD8+ CTL recruitment or activity assessments and a robust biomarker for responses to anti-PD-1/PD-L1 therapy. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.