MLKL Recombinant Rat mAb (SDT-R195),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rat
Antigen	MLKL
Synonyms	Mixed lineage kinase domain-like protein, hMLKL
Immunogen	N/A
Location	Cytoplasm, Nucleus, Membrane, Cell membrane
Accession	Q8NB16
Clone Number	SDT-R195
Antibody Type	Rat mAb
Isotype	IgG1
Application	WB, ICC
Reactivity	Hu, Ms, Rt
Purification	Protein G
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000	null
ICC	1:50	null

Background

Mixed lineage kinase domain-like (MLKL) is the executioner in the caspase-independent form of programmed cell death called necroptosis. Receptor-interacting serine/threonine protein kinase 3 (RIPK3) phosphorylates MLKL, triggering MLKL oligomerization, membrane translocation and membrane disruption [PMID: 34698396].

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.