Akt is a family of three serine-threonine kinases, Akt1, Akt2, and Akt3 [PMID: 28115590]. Akt is a serine/threonine kinase and it participates in the key role of the PI3K signaling pathway. The Akt can be activated by a wide range of growth signals and the biochemical mechanisms leading to Akt activation are well defined [PMID: 31173856].