Androgen Receptor Recombinant Rabbit mAb (SDT-R157),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	Androgen Receptor
Synonyms	AR, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4
Immunogen	N/A
Location	Nucleus
Accession	P10275
Clone Number	SDT-R157
Antibody Type	Recombinant mAb
Application	WB, IHC-P, ICC, ICFCM
Reactivity	Hu, Ms, Rt
Purification	Protein A
Concentration	0.5 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
WB	1:1000	null
IHC-P	1:1000	null
ICFCM	1:500	null
ICC	1:500	null

Background

The androgen receptor (AR), ligand-induced transcription factor, is expressed in primary prostate cancer and in metastases. AR regulates multiple cellular events, proliferation, apoptosis, migration, invasion, and differentiation. Its expression in prostate cancer cells is regulated by steroid and peptide hormones [PMID: 24384911]. The elucidation of the structures of the AR DNA binding domain (DBD) and ligand binding domain (LBD) provides a new framework for understanding the functions of this receptor and leads to the development of rational drug design for the treatment of prostate cancer [PMID: 24909511].

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.