12 months from date of receipt / reconstitution, -20 °C as supplied.
Dilution
application
dilution
species
WB
1:1000-1:5000
IHC-P
1:200
ICFCM
1:50
ICC
1:50
IP
1:25
Background
Beta III-tubulin is frequently overexpressed in human tumors and is associated with resistance to microtubule-targeting agents, tumor aggressiveness, and poor patient outcome [PMID: 34364992IF: 9.7 Q1 B1]. In prostate cancer, βIII-tubulin expression is strongly associated with both TMPRSS2: ERG rearrangement, ERG expression and PTEN deletions, three key oncogenetic features of aggressive prostate cancer [PubMed: 24378408]. Also, colorectal cancer is more aggressive in young male patients in whom testosterone elevation and activation of TUBB3 are connected with poor outcome [PubMed: 23637935].
bio-equip.cn
AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.