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Histone H3 Recombinant Rabbit mAb (SDT-266-44)
Histone H3 Recombinant Rabbit mAb (SDT-266-44)
Place of Origin:
Singapore
Brand:
Starter
Model:
S0B0079-25μl
Price:
100
Hits:
Updated:
8/25/2025
  • Product Detail
  • Company Profile

    Product Specification


    HostRabbit
    AntigenHistone H3
    SynonymsHistone H3.1
    ImmunogenSynthetic Peptide
    LocationNucleus
    AccessionP68431
    Clone NumberSDT-266-44
    Antibody TypeRecombinant mAb
    IsotypeIgG
    ApplicationWB, IHC-P, ICC, IP, IF, ICFCM, ChIP
    ReactivityHu, Ms, Rt
    Positive SampleHEK293, HeLa, NIH3T3, mouse brain, C6, rat liver, human brain, human spleen, human prostate, human breast cancer, human hepatocellular carcinoma, mouse brain, rat brain
    Predicted ReactivityBv, Dr, C.el, Pl
    PurificationProtein A
    Concentration0.5 mg/ml
    Physical AppearanceLiquid
    Storage Buffer

    PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300

    Stability & Storage

    12 months from date of receipt / reconstitution, -20 °C as supplied.

    Dilution


    applicationdilutionspecies
    WB1:5000-1:10000Hu, Ms, Rt
    IP1:50Hu, Ms, Rt
    IHC-P1:4000Hu, Ms, Rt
    ICC1:500Hu, Ms, Rt
    IF1:500Hu, Ms, Rt
    ICFCM1:500Hu, Ms, Rt
    ChIP1:20~1:50Hu, Ms, Rt

    Background

    Histone H3 is a critical component of the nucleosome, which is the basic unit of chromatin. It plays a vital role in the regulation of gene transcription and is subject to various post-translational modifications (PTMs) that affect chromatin structure and gene expression. The H3 family includes several variants, with H3.1, H3.2, and H3.3 being the most well-known. H3.1 and H3.2 are deposited during DNA replication, while H3.3 can be deposited independently of DNA replication and is incorporated throughout the cell cycle2. Post-translational modifications of Histone H3, particularly on the N- and C-terminal tails, can influence the interaction between histones and DNA, as well as with other chromatin factors. These modifications can either promote a relaxed chromatin state that allows gene transcription or lead to a condensed chromatin state that typically suppresses transcription.

    bio-equip.cn
    AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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