PAPP-A Recombinant Rabbit mAb (SDT-226-46),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	PAPP-A
Synonyms	Pappalysin-1, IGFBP-4ase
Immunogen	Recombinant Protein
Accession	Q13219
Clone Number	SDT-226-46
Antibody Type	Rabbit mAb
Reactivity	Hu
Purification	Protein A
Concentration	0.25 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:1000	null

Background

PAPP-A is a proteolytic enzyme that was discovered to increase local insulin-like growth factor (IGF) availability for receptor activation through cleavage of inhibitory IGF binding proteins (IGFBPs). Reduced IGF signaling has been associated with increased lifespan and healthspan.
Therefore, inhibition of PAPP-A represents a novel approach to indirectly decrease the availability of bioactive IGF [PMID: 28035757IF: 8.0 Q1 B1].

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.