Golgi phosphoprotein 2 (GOLPH2), also known as Golgi protein 73 (GP73) and Golgi membrane protein 1 (GOLM1), is coded by the GOLM1 gene on chromosome 9q21.33 and was first described in giant cell hepatitis [PMID: 10831838]. Structurally, GOLPH2 protein consists of a short cytoplasmic N-terminal domain, a membrane spanning region, some coiled-coil domains and a longer luminal C-terminal domain. Due to the diverse and heterogeneous function of proteins trafficking through the Golgi system the location of GOLPH2 within the Golgi membrane suggests possible roles in intracellular transportation, cell signalling, protein construction and modification or structural or maintenance tasks [PMID: 20184749].
中文
