ST2 Recombinant Rabbit mAb (SDT-094-75),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	ST2
Synonyms	sST2, Interleukin-1 receptor-like 1
Immunogen	Recombinant Protein
Location	Secreted, Membrane
Accession	Q01638
Clone Number	SDT-094-75
Antibody Type	Rabbit mAb
Application	CLIA, Sandwich ELISA
Reactivity	Hu
Purification	Protein A
Concentration	2mg/ml
Purity	>95% by HPLC
Physical Appearance	Liquid
Storage Buffer	PBS, pH 7.4, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Background

The ST2 cardiac biomarker (also known as soluble interleukin 1 receptor-like 1) is a protein biomarker of cardiac stress encoded by the IL1RL1 gene. ST2 signals the presence and severity of adverse cardiac remodeling and tissue fibrosis, which occurs in response to myocardial infarction, acute coronary syndrome, or worsening heart failure. ST2 provides prognostic information that is independent of other cardiac biomarkers such as BNP, NT-proBNP, highly sensitive troponin, GDF-15, and galectin-3. One study indicated that discrimination is independent of age, body mass index, history of heart failure, anemia and impaired kidney function or sex.sST2(Soluble ST2) is a biomarker for risk stratification in patients with heart failure (HF) and prognostic assessment. Compared with BNP and NT-proBNP, ST2 is not affected by age, factors such as BMI and renal insufficiency.Different with so many other heart markers, the level of ST2 varies rapidly with the patient's condition. This means that ST2 can help clinicians respond faster. The increase of sST2 level (> 35ng/ml) was highly correlated with the severity of heart failure which can be used to predict readmission and mortality.

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AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.