PLK1 Recombinant Rabbit mAb (SDT-R062),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	PLK1
Synonyms	STPK13
Immunogen	N/A
Location	Nucleus
Accession	P53350
Clone Number	SDT-R062
Antibody Type	Rabbit mAb
Application	WB, IHC-P, IP
Reactivity	Hu
Purification	Protein A
Concentration	1.0 mg/ml
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:200	null
WB	1:20000	null
IP	1:100	null

Background

PLK1 is a serine/threonine kinase that plays a pivotal role in cell division. Its dysregulation is tightly linked to malignant transformation. In human cancers, there is growing evidence coupling PLK1 activity to tumor development, progression, and therapy resistance. PLK1 is overexpressed in various cancers, and its expression levels correlate with poor prognosis. During cell division, the most prominent network or chestrating mitotic onset consists of the PLK1-Aurora A-Cyclin B1/CDK1 feedback loop. In this respect, PLK1 activity is reported to be a critical prerequisite for mitotic entry.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.