Home >Products> Reagents >Antibody> Biotin Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)
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Biotin Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)
Biotin Rabbit Anti-Mouse NK1.1/CD161 Antibody (S-428-32)
Place of Origin:
Singapore
Brand:
Starter
Model:
S0B5088-50T
Price:
50
Hits:
Updated:
8/25/2025
  • Product Detail
  • Company Profile

    Product Specification


    HostRabbit
    AntigenNK1.1/CD161
    SynonymsKiller cell lectin-like receptor subfamily B member 1C; CD161 antigen-like family member C; Lymphocyte antigen 55c (Ly-55c); NKR-P1.9; NKR-P1C; Natural killer cell surface protein P1-40 (NKR-P1 40); CD161c; Ly55c; Nkrp1c; Klrb1c
    ImmunogenRecombinant Protein
    LocationMembrane
    AccessionP27814
    Clone NumberS-428-32
    Antibody TypeRecombinant mAb
    IsotypeIgG
    ApplicationFCM
    ReactivityMs
    Positive SampleC57BL/6 mouse splenocytes
    PurificationProtein A
    Concentration0.2 mg/ml
    ConjugationBiotin
    Physical AppearanceLiquid
    Storage Buffer

    PBS pH7.4, 0.03% Proclin 300

    Stability & Storage12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied.

    Dilution


    applicationdilutionspecies
    FCM5渭l per million cells in 100渭l volumeMs

    Background

    NK1.1/CD161, also known as KLRB1 or NKR-P1A, is a type II transmembrane C-type lectin-like receptor expressed as a disulfide-linked homodimer on the cell membrane. It is predominantly found on the majority of natural killer (NK) cells and subsets of peripheral T cells, including both CD4+ and CD8+ T cells, particularly those with a "memory" antigenic phenotype. The expression of CD161 is specifically upregulated by IL-12 and is associated with the cytotoxic function of CD16+ NK cells. Functionally, CD161 plays a role in modulating the activation and proliferation of NK cells, inducing interferon-纬 production, and releasing cytotoxic granules. When CD161 binds to its ligand LLT1, it inhibits NK cell cytotoxicity and cytokine secretion.

    bio-equip.cn
    AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.
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