Rat Anti-Mouse CD184 Antibody (S-R670),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rat
Antigen	CD184
Synonyms	C-X-C chemokine receptor type 4; CXC-R4; CXCR-4; Fusin; Leukocyte-derived seven transmembrane domain receptor (LESTR); Pre-B-cell-derived chemokine receptor (PB-CKR); Stromal cell-derived factor 1 receptor (SDF-1 receptor); Cmkar4; Lestr; Sdf1r; Cxcr4
Location	Lysosome, Cell membrane, Cell junction
Accession	P70658
Clone Number	S-R670
Antibody Type	Rat mAb
Isotype	IgG2b,k
Application	FCM
Reactivity	Ms
Positive Sample	C57BL/6 mouse thymocytes
Purification	Protein G
Concentration	2 mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 掳C as supplied.

Dilution

application	dilution	species
FCM	1渭g per million cells in 100渭l volume	Ms

Background

CD184, also known as CXCR4 or Fusin, is a seven-transmembrane G protein-coupled receptor that plays a crucial role in various physiological processes. It is widely expressed on hematopoietic cells, including lymphoid and myeloid precursor cells, megakaryocytes, and endothelial cells. Its natural ligand is stromal cell-derived factor-1 (SDF-1), a C-X-C chemokine that induces chemotaxis and enhances intracellular signaling through calcium ion influx and MAPK activation.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.