Biotin Rat Anti-Mouse CD3 Antibody (17A2),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rat
Antigen	CD3
Synonyms	T-cell surface glycoprotein CD3 zeta chain; T-cell receptor T3 zeta chain; CD247; Cd3z; Tcrz
Location	Cell membrane
Accession	P24161
Clone Number	17A2
Antibody Type	Rat mAb
Isotype	IgG2b
Application	FCM
Reactivity	Ms
Positive Sample	C57BL/6 mouse splenocytes
Purification	Protein G
Concentration	0.2 mg/ml
Conjugation	Biotin
Physical Appearance	Liquid
Storage Buffer	PBS pH7.4, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, 2 to 8 °C as supplied.

Dilution

application	dilution	species
FCM	5μl per million cells in 100μl volume	Ms

Background

The CD3 protein is a T-cell marker, a complex of four structurally distinct membrane glycoprotein isoforms, 20-50 kDa, comprising extracellular, transmembrane and intracellular domains. CD3 is associated with an heterodimer creating the T-cell receptor (TCR). The CD3 complex is responsible for mediating signal transduction to the internal environment upon antigenic recognition by TCR, causing T-cell proliferation and release of cytokines.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.