S-RMab® CD21 Recombinant Rabbit mAb(SDT-007-47),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	CD21
Synonyms	CR2,CD3R, Complement C3d receptor, Epstein-Barr virus receptor (EBV receptor)
Immunogen	Synthetic Peptide
Location	Membrane
Accession	P20023
Clone Number	SDT-007-47
Antibody Type	Rabbit mAb
Isotype	IgG
Application	WB, IHC-P, ICC, FCM
Reactivity	Hu, Ms, Rt
Purification	Protein A
Concentration	0.08mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
IHC-P	1:1000
FCM	1:80
ICC	1:50
WB	1:200

Background

CD21 is involved in the complement system. It binds to iC3b (inactive derivative of C3b), C3dg, or C3d.B cells express CD21 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation. CD21 interacts with CD19 and on mature B cells forms a complex with CD81 (TAPA-1). The CD21-CD19-CD81 complex is often called the B cell co-receptor complex, because CD21 binds to opsonized antigens through attached C3d (or iC3b or C3dg) when the B-cell receptor binds antigen. This results in the B cell having greatly enhanced response to the antigen. Epstein-Barr virus (EBV) can bind CD21, enabling EBV to enter and infect B cells.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.