MCM3 Recombinant Rabbit mAb (SDT-048-10),Starter_specification/price/image

Product Detail
Company Profile

Product Specification

Host	Rabbit
Antigen	MCM3
Synonyms	DNA polymerase alpha holoenzyme-associated protein P1,P1-MCM3,RLF subunit beta,p102
Immunogen	Synthetic Peptide
Location	Nucleus, Chromosome, Intracellular
Accession	P25205
Clone Number	SDT-048-10
Antibody Type	Rabbit mAb
Application	WB, IHC-P, ICC, ICFCM, IP
Reactivity	Hu
Predicted Reactivity	Ms, Av, Or, Bv
Purification	Protein A
Concentration	0.5mg/ml
Conjugation	Unconjugated
Physical Appearance	Liquid
Storage Buffer	PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300
Stability & Storage	12 months from date of receipt / reconstitution, -20 °C as supplied

Dilution

application	dilution	species
ICFCM	1:500
ICC	1:500
IHC-P	1: 2000
IP	1:25
WB	1:2000

Background

DNA replication licensing factor MCM3 is a protein that in humans is encoded by the MCM3 gene. The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with, and thus is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

AntBio is a biotechnology group company dedicated to serving life sciences, aiming to help scientists accelerate research and improve work efficiency. AntBio provides comprehensive and high-quality reagent tools for basic research, drug development, and diagnosis, including research grade antibodies, proteins, biochemical reagents, and assay kits. These research tools are widely used in different segments of life science research. The group company currently consists of three brands, Absin, Starter-Bio and UA-Bio.