PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I (By similarity). It can dephosphorylate SV40 large T antigen and p53/TP53 and activates RAF1 by dephosphorylating it at ‘Ser-259'.
The Abbkine PP2AA Rabbit Polyclonal Antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen anddetects endogenous levels of PP2AA protein The antibody has been validaed in WB, ELISA and reacts with Human, Mouse, Rat samples.
Abbkine supplies below price/size: $100/30μl, $220/100μl, $360/200μl of Rabbit Anti-PP2AA Polyclonal Antibody at https://www.abbkine.com/product/pp2aa-polyclonal-antibody-abp59976/.
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