ADGRV1 encodes a member of the G-protein coupled receptor superfamily. The encoded protein contains a 7-transmembrane receptor domain, binds calcium and is expressed in the central nervous system. Mutations in ADGRV1 are associated with Usher syndrome 2 and familial febrile seizures. Several alternatively spliced transcripts have been described.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-p 1:50-300.
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