CACNG8 (Calcium Voltage-Gated Channel Auxiliary Subunit Gamma 8) is a Protein Coding gene. Diseases associated with CACNG8 include Dilated Cardiomyopathy. Among its related pathways are Arrhythmogenic right ventricular cardiomyopathy (ARVC) and Fc-GammaR Pathway. The protein encoded by CACNG8 is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. CACNG8 is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type II TARP and a calcium channel gamma subunit. The mRNA for CACNG8 is believed to initiate translation from a non-AUG (CUG) start codon.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000 ELISA 1:5000-20000.
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