DDR2 (Discoidin Domain Receptor Tyrosine Kinase 2) is a Protein Coding gene. Diseases associated with DDR2 include Spondylometaepiphyseal Dysplasia, Short Limb-Hand Type and Squamous Cell Carcinoma. Among its related pathways are Akt Signaling and Nanog in Mammalian ESC Pluripotency. DDR2 encodes a member of the discoidin domain receptor subclass of the receptor tyrosine kinase (RTKs) protein family. RTKs play a key role in the communication of cells with their microenvironment. The encoded protein is a collagen-induced receptor that activates signal transduction pathways involved in cell adhesion, proliferation, and extracellular matrix remodeling. This protein is expressed in numerous cell types and may alos be involved in wound repair and regulate tumor growth and invasiveness. Mutations in DDR2 are the cause of short limb-hand type spondylometaepiphyseal dysplasia.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-p 1:50-200, ELISA 1:10000-20000.
DDR2 Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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