Human Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) ELISA Kit,Abbkine_specification/price/image

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NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response.The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Human Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) ELISA Kit employs a two-site sandwich ELISA to quantitate NFATC1 in samples. An antibody specific for NFATC1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyNFATC1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for NFATC1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of NFATC1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.