Human Platelet endothelial cell adhesion molecule (PECAM1) ELISA Kit,Abbkine_specification/price/image

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CD31 is a cluster of differentiation molecule. It is also called PECAM-1 for platelet endothelial cell adhesion molecule. It plays a key role in removing aged neutrophils from the body. Macrophages palpate any passing neutrophil and have to decide whether the cell is healthy or has to be ingested. In humans, the gene encoding CD-31 is found on chromosome 17.If a neutrophil is dying, it will have phosphatidyl serine in its plasma membrane. Both the neutrophil and the macrophage express CD-31 on their membranes, and, during the testing process, these CD-31 molecules bind the two cells together. If the neutrophil is healthy, it will now fire a signal to the macrophage, and the CD-31 molecules will detach. The neutrophil is now free.

Human Platelet endothelial cell adhesion molecule (PECAM1) ELISA Kit employs a two-site sandwich ELISA to quantitate PECAM1 in samples. An antibody specific for PECAM1 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPECAM1 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PECAM1 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PECAM1 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Platelet endothelial cell adhesion molecule (PECAM1) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.