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Bio Excellence international Tech Co.,Ltd has been acting as sole agent for the sale of flexcell products for more than ten years,Bio Excellence can provide free technical guidance for flexcell tension, compression, fluid shear products, user site installation as well as training, until the user can use them without limiting number of training times.If you have any questions, please do not hesitate to contact us.

flexcell FX-5000™ Compression System (FX-5000C)

Apply compression to tissue samples or 3-D cell-seeded constructs

Apply cyclic or static compression to cells in 3D culture.
 Computerized, pressure-operated instrument that
applies a defined controlled, static or variable
duration cyclic compression to cells growing in
vitro.
 Utilizes regulated air pressure to deflect flexiblebottomed
BioPress™ culture plates (page 24)
compressing a tissue sample or 3D culture
between a piston and a stationary platen
(Fig. 11).
 Can apply up to 14 pounds of applied force.
 Simulate in vivo tissue forces and frequencies in
cells from muscle, lung, heart, blood vessels,
skin, tendon, ligament, cartilage, and bone.
 Contains state-of-the-art digital valve to
automatically regulate and maintain pressure for a
specified compression regimen.
 Multiple frequency, amplitude and waveform
changes can be programmed in one regimen
(Fig. 10).
 Waveforms available: static, sinusoidal, heart
stimulation, triangular, square, custom.
 Drives up to four independent FlexLink® remote
compression and/or tension controllers.
 Works with StagePresser™ microscopy device
(see below).
 FX-5000™ Compression System includes:
Figure 9. FX-5000™ Compression System
Figure 10. Waveform plot showing a sine
wave with various frequency and amplitude
changes
Figure 11. Application of unconfined
compression to cells in a well of a BioPress™
culture plate
- Host computer with flat panel monitor
- FlexSoft FX-5000™ software
- FX5K™ Compression FlexLink®
- Biopress™ Baseplate and four gaskets
- Compression clamping system
- Four BioPress™ culture plates
- Tubing and quick disconnects

Flexcell BioPress Compression Plates>>More

Works with a Flexcell® Compression System to simulate biological compression conditions using pressure to deform tissue samples or cells cultured in a matrix.

• Uses positive pressure to compress tissue samples or cell-seeded constructs between a piston and stationary platen in the Biopress® culture plate yielding up to 14 lb. of applied force
• Platens are reusable and autoclavable. They are sold separately and as part of the FX-5000C Compression System
• Biopress culture plates are available individually or in case quantity of 40 plates

StagePresser® -Real-time observation of pressure loading under microscope

A single-well embodiment of the compression apparatus designed to allow the user to detect signaling responses to compression.

• Designed to compress cells between a piston and stationary platen using the FX-5000™ Compression System
• View compressed cells in real time with an upright microscope

Schematic of how compression is applied to tissue samples or 3D cell cultures in a StagePresser.