Candida albicans is a type of yeast that is commonly used as a model organism for biology. It is generally referred to as a dimorphic fungus since it grows both as yeast and filamentous cells. However it has several different morphological phenotypes that are discussed more in detail in the chapter on Morphology. Different morphological forms of Candida albicans: the scale bar is 50 µm. It is a common member of human gut flora and does not seem to proliferate outside mammalian hosts. It is detectable in the gastrointestinal tract and mouth in 40-60% of healthy adults. It is usually a commensal organism, but can become pathogenic in immunocompromised individuals under a variety of conditions. It is one of the few species of the Candida genus that cause the infection candidiasis in humans. Overgrowth of the fungus results in candidiasis (candidosis). Candidiasis is for example often observed in HIV-infected patients. C. albicans is the most common fungal species isolated from biofilms either formed on (permanent) implanted medical devices or on human tissue. C. albicans, together with C. tropicalis, C. parapsilosis and C. glabrata, is responsible for 50–90% of all cases of candidiasis in humans. A mortality rate of 40% has been reported for patients with systemic candidiasis due to C. albicans. Estimates range from 2800 to 11200 deaths caused annually in the USA due to C. albicans causes candidiasis.

Human Candida albicans (C.albicans) ELISA Kit employs a two-site sandwich ELISA to quantitate C.albicans in samples. An antibody specific for C.albicans has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyC.albicans present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for C.albicans is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of C.albicans bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Candida albicans (C.albicans) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

Find more details at http://www.abbkine.com/product/human-candida-albicans-c-albicans-elisa-kit-kte62519/

Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.