Human Proteasome subunit alpha type-7 (PSMA7) ELISA Kit,Abbkine_specification/price/image

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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. PSMA7 has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication.This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9.

Human Proteasome subunit alpha type-7 (PSMA7) ELISA Kit employs a two-site sandwich ELISA to quantitate PSMA7 in samples. An antibody specific for PSMA7 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyPSMA7 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for PSMA7 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of PSMA7 bound in the initial step. The color development is stopped and the intensity of the color is measured.

Human Proteasome subunit alpha type-7 (PSMA7) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

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Abbkine Scientific Co., Ltd. was founded by a number of scientists and marketing experts in the field of life science in California in 2012. With growing demands from Asia Pacific, it move its headquarters to China. Combining cutting edge technology from United States with China's manufacturing engineering and cost advantages, we aim to provide innovative, high quality assay kits, recombinant proteins, antibodies and other research tools to accelerate life science fundamental research, drug discovery, etc.