Eleven novel TPGs were discovered: DCP1A (decapping enzyme homologue A), (trinucleotide repeat containing 18), LAMC3 (laminin, g-3), NEBL (nebulette), NRIP3 (nuclear receptor interacting protein 3), C2CD3 (C2 calciumdependent domain containing 3), UBE4A (ubiquitination factor from the gel and subjected to DNA sequence analyses to obtain the patient-specific fusion sequences. The DCP1A gene encodes a homologue of the DCP1 decapping enzyme, involved in mRNA degradation.15 The protein localizes in the mRNA processing body (P-body) that regulates degradation and abundance of RNA molecules (RNA decay). For TNRC18, no function is known. LAMC3 is a nonbasement membrane-associate filamentous protein that is downregulated or deleted in carcinomas.
Human Trinucleotide repeat-containing gene 18 protein (TNRC18) ELISA Kit employs a two-site sandwich ELISA to quantitate TNRC18 in samples. An antibody specific for TNRC18 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyTNRC18 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNRC18 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNRC18 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Human Trinucleotide repeat-containing gene 18 protein (TNRC18) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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