Microtubule-associated protein 6 is a microtubule-associated protein. It is calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene.Mammalian cells often contain abundant subpopulations of microtubules that are stable to both drug- and cold temperature-induced disassembly. Such microtubules are apparently universal in the neurite extensions of neuronal cells.The protein, called stable tubule-only polypeptide (STOP) by them, is a 100.5-kD polypeptide. The central region of the predicted 952-amino acid polypeptide contains 5 tandem repeats of 46 amino acids. STOP also contains a putative SH3-binding motif near its N terminus.
Chicken Microtubule-associated protein 6 (MAP6) ELISA Kit employs a two-site sandwich ELISA to quantitate MAP6 in samples. An antibody specific for MAP6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and anyMAP6 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for MAP6 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of MAP6 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Chicken Microtubule-associated protein 6 (MAP6) ELISA Kit listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
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