Sp1 transcription factor encoded by Sp1 transcription factor is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. Sp1 transcription factor is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of Sp1 transcription factor, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for Sp1.
Phospho-Sp1 (T739) Polyclonal Antibody detects endogenous levels of Sp1 protein only when phosphorylated at T739.
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB: 1:500-1:2000, IHC-p: 1:100-1:300, ELISA: 1:5000. Not yet tested in other applications.
Sp1 (phospho Thr739) Polyclonal Antibody product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Find more details at http://www.abbkine.com/product/sp1-phospho-thr739-polyclonal-antibody-abp50404.
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