1, About Triple Quad 5500 System（MS）

Designed to deliver high levels of sensitivity and robustness for even the most complex and demanding matrices.

2, Specifications

1> For research use only. Not for use in diagnostic procedures.

The Triple Quad 5500 LC-MS/MS System is designed to deliver high levels of sensitivity and robustness for even the most complex and demanding matrices. The Triple Quad 5500  LC-MS/MS exceeds the performance required by even the most demanding DMPK and ADMET studies and excels at multi-component quantitation required by environmental, targeted quantitative proteomics, clinical research, and food and beverage applications. Built from the ground up on new, fast eQ™ Electronics, the LC-MS/MS system combines new-and-improved patented technologies with the powerful Analyst Software.

1) Robust, high-throughput platform for all stages of pharmaceutical development

2) Excellent results for highly-multiplexed peptide quantitation

3) Unequalled accuracy and precision for quantitative analysis

4) Smaller footprint

5) Lowest limits of detection available for DMPK and ADMET studies

2> Next-generation EQ Electronics for fast LC

The new system uses the next-generation EQ Electronics (i.e. polarity switching in 50 msec), so now the compounds with vastly different functional groups can be measured in a single pass without sacrificing performance. The new electronics also provide improved performance at ultra-low MRM dwell times for improved support of fast LC and narrow peak widths.

Figure 1: 1300 or more matrix injections with low %CV.

3> Flexible and integrated system

The standard ionization source, the Turbo V Source, allows reliable routine operation with either the TurboIonSpray Probe or the heated nebulizer probe. The optional DuoSpray Source provides an ideal tool for faster method development and increased throughput. Another option, the PhotoSpray Source for atmospheric-pressure photoionization increases your possibilities for analysis.

4> New, patented QJet 2 Ion Guide improves robustness

The patented QJet 2 Ion Guide design yields improved ion containment and operates at higher pressures providing better collisional focusing to enhance ion transmission for ultimate sensitivity. The new design also reduces the gas load, allowing the turbopump to run cooler in its ideal operating range. The built-in diverter valve simplifies waste redirection to help maintain robustness.

5> High-throughput operation

The Triple Quad 5500 System continues the tradition of rugged, reliable triple quadrupole systems. Advanced automation features enable continuous duty operation in regulated, high-throughput laboratories.

6> Expert results – even for non-experts

The Triple Quad 5500 System makes it easy for you to get the answers you need – even if you're just getting into mass spectrometry. From automated methods development to quick, simple routine maintenance, it is not only the most powerful triple quadrupole instrument available, it's the easiest to use too.