Login    Join free Add to favorites    中文
Home >Products> Physiology | Pharmacology | Neurology >Electrophysiology> Psalmotoxin 1
Physiology | Pharmacology | Neurology:  Electrophysiology   Microtome   Animal Experimental Equipment   Animal Cages  
Psalmotoxin 1
Place of Origin:
France
Brand:
Smartox
Model:
0.1 mg
Supplier:
Smartox Biotech
Price:
135 €
Hits:
1433 
Updated:
6/18/2014
Related Products | Other Products | Related Suppliers
  • Product Detail
  • Company Profile
    Psalmotoxin 1 - PcTx1, ASIC1a selective blocker Psalmotoxin-1 (PcTx1, Pi-theraphotoxin-Pc1a) has been isolated from the venom of the Spider Psalmopoeus cambridgei (Trinidad chevron tarantula). PcTx1 is known to block potently (IC50 = 1 nM) and selectively the H+-gated sodium channel ASIC1a (acid-sensitive ion channel 1a). The blockage is rapid and reversible. PcTx1 can distinguish between the two ASIC1 splice variants ASIC1a and ASIC1b. PcTx1 loses its capacity to block ASIC1a as soon as this subunit is associated with another member of the family (ASIC2a or ASIC3). PcTx1 demonstrates an analgesic effect in acute and neuropathic pain models. PcTx1 technical information AA sequence: Glu-Asp-Cys3-Ile-Pro-Lys-Trp-Lys-Gly-Cys10-Val-Asn-Arg-His-Gly-Asp-Cys17-Cys18-Glu-Gly-Leu-Glu-Cys23-Trp-Lys-Arg-Arg-Arg-Ser-Phe-Glu-Val-Cys33-Val-Pro-Lys-Thr-Pro-Lys-Thr Disulfide bonds: Cys3-Cys18, Cys10-Cys23 and Cys17-Cys33 Length (aa): 40 Formula: C200H312N62O57S6 Molecular Weight: 4690.82 Da Appearance: White lyophilized solid Solubility: water and saline buffer CAS number: not available Source: Synthetic Purity rate: > 98% http://www.smartox-biotech.com/en/asic-channel/260-psalmotoxin1
    bio-equip.cn
    Smartox Biotechnology is specialized in supplying the life science research community with biological materials issued from animal's venoms. The company offers venom peptides for basic research and drug discovery solutions based on its venom collection and expertise.
Request Information
Request Information: yes no
Request Quotation: yes no
refresh

I agree to share my inquiry with the other matching suppliers.

Send Now
Request Information

* Name:
Job Title:
* Tel:
Fax:
* E-mail:
Postcode:
Institution/Company:
Address:
* Country:
Request Information:
 yes no
Request Quotation:
 yes no
* Message:
* Verification Code:
 refresh
I agree to share my inquiry to the other matching suppliers.


Other Products

Recently viewed products
SiteMap
Copyright(C) 2006-2025 Bio-Equip E-mail:web@bio-equip.cn Tel:+86-17717806891 (Wechat)