Leiurotoxin 1 / Scyllatoxin, SK channels blocker
Leiurotoxin 1 (scyllatoxin) is a neurotoxin that was originally isolated from Leiurus quinquestriatus hebraeus. Leuirotoxin binds and blocks SK channels (small conductance Ca2+-activated K+ channels) in the brain and spinal cord and inhibits them.
Leiurotoxin 1 / Scyllatoxin technical information
AA sequence: Ala-Phe-Cys3-Asn-Leu-Arg-Met-Cys8-Gln-Leu-Ser-Cys12-Arg-Ser-Leu-Gly-Leu-Leu-Gly-Lys-Cys21-Ile-Gly-Asp-Lys-Cys26-Glu-Cys28-Val-Lys-His-NH2
Disulfide bonds between: Cys3-Cys21, Cys8-Cys 26 and Cys12-Cys28
Length (aa) : 31
Formula: C142H237N45O39S7
Molecular Weight: 3424.1 Da
Appearance: White lyophilized solid
Solubility: water and saline buffer
CAS number: [116235-63-3]
Source: Synthetic
Purity rate: > 95%
http://www.smartox-biotech.com/en/potassium-channel/187-leiurotoxin-1
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