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Iberiotoxin
Place of Origin:
France
Brand:
Smartox
Model:
0.1 mg
Supplier:
Smartox Biotech
Price:
135 €
Hits:
1376 
Updated:
6/18/2014
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  • Product Detail
  • Company Profile
    Iberiotoxin, Blocker of high conductance Ca2+-activated K+ channel Iberiotoxin (IbTx) is a toxin that was originally isolated from Buthus tamulus scorpion venom. Iberiotoxin inhibits selectively the high conductance Ca2+-activated K+ channel (KCa1.1) at nanomolar concentrations (IC50 ~2 nM). This toxin does not affect other types of calcium-dependent or voltage-dependent K+ channels. Iberiotoxin is a valuable tool to study specifically Maxi-K channels. Iberiotoxin technical information AA sequence: pGlu-Phe-Thr-AspVal-Asp-Cys-Ser-Val-Ser-Lys-GIu-Cys-Trp-Ser-Val-Cys-Lys-Asp-Leu-Phe-Gly-Val-Asp-Arg-Gly-Lys-Cys-Met-Gly-Lys-Lys-Cys-Arg-Cys-Tyr-GIn-OH Disulfide bridges: Cys7-Cys28, Cys13-Cys33, Cys17-Cys35 Length (aa): 37 Formula: C179H274N50O55S7 Molecular Weight: 4230.8 Da Appearance: White lyophilized solid Solubility: water and saline buffer CAS number: 129203-60-7 Source: Synthetic Purity rate: > 95 % http://www.smartox-biotech.com/en/potassium-channel/227-iberiotoxin
    bio-equip.cn
    Smartox Biotechnology is specialized in supplying the life science research community with biological materials issued from animal's venoms. The company offers venom peptides for basic research and drug discovery solutions based on its venom collection and expertise.
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