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GaTx1
Place of Origin:
France
Brand:
Smartox
Model:
0.1 mg
Supplier:
Smartox Biotech
Price:
200
Hits:
1112 
Updated:
6/18/2014
  • Product Detail
  • Company Profile
    GaTx1, Selective blocker of CFTR channels The GaTx1 peptide was originally isolated from the venom of Leiurus quinquestriatus hebraeus. GaTx1 is a potent and selective inhibitor of CFTR, an anion selective channel belonging to the ABC transporter superfamily. It was shown to block CFTR channels in a state dependent manner by acting from the internal face of the channel and it is supposed to be a non competitive inhibitor of ATP-dependent channel gating. GaTx1 is a valuable tool to explore the function of CFTR. GaTx1 technical information AA sequence: Cys1-Gly-Pro-Cys4-Phe-Thr-Thr-Asp-His-Gln-Met-Glu-Gln-Lys-Cys15-Ala-Glu-Cys18-Cys19-Gly-Gly-Ile-Gly-Lys-Cys25-Tyr-Gly-Pro-Gln-Cys30-Leu-Cys32-Asn-Arg-NH2 Disulfide bonds between: Cys1-Cys18, Cys4-Cys25, Cys15-Cys30, and Cys19-Cys32 Length (aa): 34 Formula: C147H224N46O47S96 Molecular Weight: 3674.2 Da Appearance: White lyophilized solid Solubility: water and saline buffer CAS number: not available Source: Synthetic Purity rate: > 98 % http://www.smartox-biotech.com/en/chloride-channel/265-gatx1
    bio-equip.cn
    Smartox Biotechnology is specialized in supplying the life science research community with biological materials issued from animal's venoms. The company offers venom peptides for basic research and drug discovery solutions based on its venom collection and expertise.
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