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Omega-conotoxin MVIIA
Place of Origin:
France
Brand:
Smartox
Model:
0.1 mg
Supplier:
Smartox Biotech
Price:
100 €
Hits:
1534 
Updated:
6/18/2014
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  • Product Detail
  • Company Profile
    ω-Conotoxin MVIIA / Omega-conotoxin MVIIA, Blocker of N-type voltage-gated calcium channels ω-Conotoxin MVIIA (omega-conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). ω-conotoxin MVIIA blocks N-type voltage-gated calcium channels (Cav2.2/CACNA1B). ω-conotoxin MVIIA is available as analgesic drug under the name Prialt®. It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals. ω-Conotoxin MVIIA technical information AA sequence: Cys1-Lys-Gly-Lys-Gly-Ala-Lys-Cys8-Ser-Arg-Leu-Met-Tyr-Asp-Cys15-Cys16-Thr-Gly-Ser-Cys20-Arg-Ser-Gly-Lys-Cys25-NH2 Disulfide bonds: Cys1-Cys16, Cys8-Cys20 and Cys15-Cys25 Length (aa): 25 Formula: C102H172N36O32S7 Molecular Weight: 2639.18 Da Appearance: White lyophilized solid Solubility: water and saline buffer CAS number: [107452-89-1] Source: Synthetic Purity rate: > 97 % See also: conotoxin MVIIC, conotoxin GVIA, conotoxin SO3 http://www.smartox-biotech.com/en/calcium-channel/95--conotoxin-mviia
    bio-equip.cn
    Smartox Biotechnology is specialized in supplying the life science research community with biological materials issued from animal's venoms. The company offers venom peptides for basic research and drug discovery solutions based on its venom collection and expertise.
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